Results & Side Effects

The floor is lava, but her skin is

mild to moderate eczema (atopic dermatitis) for ages 2-5

Not an actual patient. Symptoms illustrated.

ZORYVE rhymes with “BELIEVE”

ZORYVE was tested as a once-daily, stand-alone treatment for 4 weeks in a clinical study involving 652 children ages 2–5 with mild to moderate eczema. 436 children used ZORYVE, and 215 children used an inactive cream (a cream not containing the active ingredient).

Clear or Almost Clear skin

25% of children using ZORYVE had Clear or Almost Clear skin in 4 weeks vs 11% of children using inactive cream

Additional Results*

These assessments were exploratory endpoints and reported by caregivers, which means these findings can help describe patterns but aren’t meant for definitive conclusions. Individual results may vary.

Itch Reduction

35%

of 347 children using ZORYVE once daily reported itch reduction within 4 weeks vs 18% of 160 children using inactive cream.

Itch After Application

Some children experienced less itching within 24 hours after the first ZORYVE application.

*Itch levels were tracked and reported by caregivers of children daily. This technique may need more testing to confirm its accuracy in children under 12 years old. Results may vary.

Clearer skin you can see.

Actual clinical trial patients. Results may vary.

Ankle

3 YEAR OLD

Day 1
Ankle of clinical trial patient before starting treatment with ZORYVE
Ankle of clinical trial patient 1 week after ZORYVE treatment
Ankle of clinical trial patient 4 weeks after ZORYVE treatment

Inside Elbow

3 YEAR OLD

Day 1
Inside Elbow of clinical trial patient before starting treatment with ZORYVE
Inside Elbow of clinical trial patient 1 week after ZORYVE treatment
Inside Elbow of clinical trial patient 4 weeks after ZORYVE treatment

Hand

3 YEAR OLD

Day 1
Hand of clinical trial patient before starting treatment with ZORYVE
Hand of clinical trial patient 1 week after ZORYVE treatment
Hand of clinical trial patient 4 weeks after ZORYVE treatment

Ankle

3 YEAR OLD

Day 1
Ankle of clinical trial patient before starting treatment with ZORYVE
Ankle of clinical trial patient 1 week after ZORYVE treatment
Ankle of clinical trial patient 4 weeks after ZORYVE treatment

Chest

2 YEAR OLD

Day 1
Chest of clinical trial patient before starting treatment with ZORYVE
Chest of clinical trial patient 1 week after ZORYVE treatment
Chest of clinical trial patient 4 weeks after ZORYVE treatment

Foot

2 YEAR OLD

Day 1
Foot of clinical trial patient before starting treatment with ZORYVE
Foot of clinical trial patient 1 week after ZORYVE treatment
Foot of clinical trial patient 4 weeks after ZORYVE treatment

Thigh

2 YEAR OLD

Day 1
Thigh of clinical trial patient before starting treatment with ZORYVE
Thigh of clinical trial patient 1 week after ZORYVE treatment
Thigh of clinical trial patient 4 weeks after ZORYVE treatment

Back Of Knee

4 YEAR OLD

Day 1
Back of knee of clinical trial patient before starting treatment with ZORYVE
Back of knee of clinical trial patient 1 week after ZORYVE treatment
Back of knee of clinical trial patient 4 weeks after ZORYVE treatment

Wrist And Hand

4 YEAR OLD

Day 1
Wrist and Hand of clinical trial patient before starting treatment with ZORYVE
Wrist and Hand of clinical trial patient 1 week after ZORYVE treatment
Wrist and Hand of clinical trial patient 4 weeks after ZORYVE treatment

Before starting treatment with ZORYVE in the clinical trial, 52% of children previously used topical steroids that did not help or were not the right fit for them.

Does ZORYVE burn or sting?

Stinging or burning that caused discomfort was reported in less than 1% of children (age 2–5) within the first 10–15 minutes of applying ZORYVE vs 3.6% of children using inactive cream.

Most common side effects from clinical trials

These are not all the possible side effects of ZORYVE cream. Call your provider for medical advice about side effects.

ZORYVE is safe and can be used anywhere on the skin affected with eczema and for however long your child needs it.