About ZORYVE

Eczema cream
that feels like
skincare

without steroids

mild to moderate eczema (atopic dermatitis) for age 6+mild to moderate eczema (atopic dermatitis) for age 6+

Not an actual patient. Symptoms illustrated.

2025 Allure Best of Beauty Award Winner
2024 Glamour Beauty & Wellness Awards

Award-winning Eczema TreatmentZORYVE cream 0.15% for age 6+

ZORYVE® (roflumilast) cream 0.15%
2025 Allure Best of Beauty Award Winner
2024 Glamour Beauty & Wellness Awards

Award-winning Eczema TreatmentZORYVE cream 0.15% for age 6+

  • ONCE-DAILY

  • NOT A STEROID

  • GENTLE FORMULATION

ZORYVE cream 0.15% is a topical prescription medicine used on the skin to treat
mild to moderate eczema (atopic dermatitis) in people 6 years of age or older.

ZORYVE rhymes with “BELIEVE”

Not an actual patient.
Symptoms illustrated.

Skin-friendly eczema cream
you can feel good about

  • Feels soft and smooth, like skincare

  • Absorbs quickly with no sticky or greasy feeling

  • Formulated without fragrances or known irritants

  • Designed for long-term use, without disrupting the skin barrier

  • Not a pill or an injection

ZORYVE is included in the American Academy of Dermatology (AAD) Guidelines:

ZORYVE 0.15% is strongly recommended as a treatment option for adults with mild to moderate atopic dermatitis by the AAD 2025 guidelines. Ask your doctor if ZORYVE is right for you.

ZORYVE can be applied anywhere, on every nook and cranny, including:

  • Face

  • Eyelids

  • Torso

  • Hands

  • Feet

  • Places where skin touches skin like elbow creases, knee creases, wrists, and ankles

ZORYVE is for use on the skin only. Do not use ZORYVE in or on your eyes, mouth, or vagina.

What makes ZORYVE different?

In adults and children, atopic dermatitis can happen when the immune system becomes too active and the skin barrier doesn't work the way it should.

An enzyme in the body called phosphodiesterase-4 (PDE4) can play a role in this when it works too much. This can lead to symptoms like redness, itching, and inflammation.

The active ingredient in ZORYVE is roflumilast, a PDE4 inhibitor that helps reduce inflammation associated with the skin, which may relieve symptoms of eczema.

Not an actual patient.
Symptoms illustrated.

Real ZORYVE 0.15% patient Laney

Many things caused my breakouts, such as scented lotions, the winter, turtlenecks, itchy clothing, and perfumes. I often thought, ‘the world is a trigger and I’m living in it.’ It didn’t matter where I was—everywhere, not just one spot—it could happen anywhere on my body.

Laney, a real ZORYVE cream 0.15% patient

SEE REAL PATIENT STORIES

Results may vary.