ZORYVE® (roflumilast) 0.3% cream
The CREAM that can

The steroid-free topical cream that can
help clear plaque psoriasis everywhere.

National Psoriasis Foundation Recognized

First topical prescription medication recognized by the National Psoriasis Foundation

Not an actual patient. Symptoms illustrated.
ZORYVE is for use on the skin only. Do not use ZORYVE in or on your eyes, mouth, or vagina.For more information about the National Psoriasis Foundation Recognized seal, please go to psoriasis.org/seal-of-recognition-program/
ZORYVE  (rhymes with “BELIEVE”)
is a steroid-free topical cream
that works across body areas affected by plaque psoriasis.
Cream
Foam
Treatment for plaques and itch, without steroids

ZORYVE cream is non-greasy and is designed to spread easily and absorb quickly anywhere on the skin, wherever you have plaque psoriasis.

ZORYVE can be used anywhere on the body, including*:
Face
Eyelids
Elbows
In skin folds
Exterior genital
areas like the groin
*Do not use ZORYVE in or on your eyes, mouth, or vagina.
ZORYVE cream
is designed with skin in mind
  • Steroid-free
  • Once-daily
  • Spreads easily
  • Fragrance-free, gluten-free, and vegan
  • Non-greasy
  • Leaves no residue
  • Absorbs quickly
Not an actual patient.
Symptoms illustrated.
Actor Portrayal.
What is ZORYVE?

ZORYVE contains roflumilast, a phosphodiesterase-4 (PDE4) inhibitor.

Plaque psoriasis is a condition where the immune system is overactive. Enzymes like PDE4 can play a role in this. When PDE4 works too much, the results can be associated with the symptoms of plaque psoriasis.

ZORYVE works as a PDE4 inhibitor, a molecule that manages PDE4 activity, to:

  • Decrease inflammation in the skin
  • Balance the skin's immune system
Reviews from patients who have used ZORYVE cream

112 people with plaque psoriasis were identified by their healthcare professional to sample once-daily ZORYVE for 30 days and share their experience.†

Features people liked about ZORYVE:

  • Improvement in plaques
  • One product for all areas
  • Steroid-free
  • Once-daily dosing
  • Itch relief

People were asked to identify what they liked most about ZORYVE from a list of 7 product features. Additional features that patients liked were ease of application and cream feel and consistency.

†Those surveyed via SMS received nominal compensation for completing the survey.

81%
said they would continue
using ZORYVE if prescribed
Actor portrayal.
My doctor also told me that it works in sensitive areas, like the face or skin folds, but also in tough areas like the knees and elbows, where I tend to have a lot of issues. 
Andrew, a real ZORYVE cream patient
SEE REAL PATIENT STORIES
Results may vary.
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Talk with your
dermatology provider
Not sure how to talk about your plaque
psoriasis? See our helpful Appointment Guide.
USE THE GUIDE
Next: Before and after photos
See Results