ZORYVE® (roflumilast) 0.3% cream
ZORYVE cream can help
deliver rapid results
EVERYWHERE.
Not an actual patient. Symptoms illustrated.
ZORYVE is for use on the skin only. Do not use ZORYVE in or on your eyes, mouth, or vagina.
ZORYVE  (rhymes with “BELIEVE”)
is a steroid-free topical cream for people 6 years and older that can
be used anywhere on the skin (or body) where psoriasis appears, including elbows, knees, skin folds, and face.
Cream
Foam
ZORYVE cream can help clear plaques and relieve itch

ZORYVE is a once-daily, steroid-free cream. It was studied in two clinical trials, with 576 people treated with ZORYVE, and 305 people treated with inactive cream (a cream not containing the active ingredient).

After using ZORYVE for 8 weeks across affected areas on the skin:

In Skin Folds

70% of people achieved clearer skin in these areas

Out of 116 people using ZORYVE once daily vs 16% of 63 people using inactive cream

Across Areas of
the Body

40% of people achieved clearer skin

Out of 576 people using ZORYVE once daily vs 7% of 305 people using inactive cream

Itch Relief

69% of people experienced itch relief

Out of 447 people using ZORYVE once daily vs 31% of 231 people using inactive cream

Elbow

Knee

Armpit

Under breast

Elbow

Day 0
Image of elbow at day 0
Week 2
Image of elbow at week 2
Week 4
Image of elbow at week 4
Week 8
Image of elbow at week 8

Knee

Day 0
Image of knee at day 0
Week 2
Image of knee at week 2
Week 4
Image of knee at week 4
Week 8
Image of knee at week 8

Armpit

Day 0
Image of armpit at day 0
Week 2
Image of armpit at week 2
Week 4
Image of armpit at week 4
Week 8
Image of armpit at week 8

Under breast

Day 0
Image of under breast at day 0
Week 2
Image of under breast at week 2
Week 4
Image of under breast at week 4
Week 8
Image of under breast at week 8
Actual clinical trial patient. Results may vary.
HOW LONG CAN I USE ZORYVE? ZORYVE is steroid-free and designed for long-term, everyday use.
Most Common Side Effects
SIDE EFFECTS ZORYVE CREAM
in 576 people		 INACTIVE CREAM
in 305 people
Diarrhea 3.1% 0%
Headache 2.4% 1%
Trouble sleeping 1.4% 0.7%
Nausea 1.2% 0.3%
Application site pain 1% 0.3%
Upper respiratory tract infections 1% 0.3%
Urinary tract infections (UTIs) 1% 0.7%
These are not all the possible side effects of ZORYVE cream. Call your provider for medical advice about side effects.
In my experience I’ve tried lots of different creams so when I was introduced to ZORYVE I didn’t want to have high expectations. I had a great experience with it because it worked so well for me. 
Christy, a real ZORYVE cream patient
SEE REAL PATIENT STORIES
Results may vary.
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Talk with your
dermatology provider
Not sure how to talk about your plaque
psoriasis? See our helpful Appointment Guide.
USE THE GUIDE
Next: Applying ZORYVE
is as easy as 1-2-3
HOW TO APPLY